The book deciphers the language that the cancer cells use to interact with its microenvironment to facilitate proliferation and survival. Cancer cells are champion survivors and they hijack multiple mechanisms of the host. This book includes a brief history of cancer followed by a description and artistic representation of four novel traits exploited by cancer cells namely, dedifferentiation, epigenetics, microbiome, and nerves. The book weaves the traits of cancer cells around the latest cancer research.